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Haploid genotype - cdc18+(wild type)[Overexpression]

Genotype summary

Description
cdc18+(wild type)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc18 (SPBC14C8.07c)MCM loadercdc18+wild typewild_typeOverexpression

Annotation

Single locus phenotype

FYPO:0004596 - abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete rereplication

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FYPO:0001425 - abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication

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FYPO:0001407 - decreased cell population growth on glucose carbon source

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0001128 - decreased septation index

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000158 - DNA content increased during vegetative growth

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FYPO:0005773 - elongated mononucleate aseptate vegetative cell

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FYPO:0001122 - elongated vegetative cell

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FYPO:0000344 - enlarged nucleus during vegetative growth

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FYPO:0000836 - increased protein level

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FYPO:0004961 - increased protein localization to chromatin at replication origin

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FYPO:0004598 - increased protein localization to chromatin during mitotic G2 phase

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FYPO:0002994 - increased protein localization to chromatin during mitotic S phase

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FYPO:0002083 - inviable swollen elongated cell with enlarged nucleus

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FYPO:0000012 - mitotic G2/M phase transition delay

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FYPO:0004597 - replication origin firing during mitotic G2 phase

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FYPO:0001492 - viable elongated vegetative cell

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