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Haploid genotype - cdc18deltaCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa) cdt1-S360A(aa)[Overexpression]

Genotype summary

Description
cdc18deltaCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa) cdt1-S360A(aa)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc18 (SPBC14C8.07c)MCM loadercdc18deltaCDK1-5T4A,T10A,T46A,T60A,T101A,T104A,T134Aamino_acid_mutationNot assayed or wild type
cdt1 (SPBC428.18)DNA replication licensing factor Cdt1cdt1-S360AS360Aamino_acid_mutationOverexpression

Annotation

Multi-locus phenotype

FYPO:0001425 - abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication

References:

Genes:

FYPO:0002083 - inviable swollen elongated cell with enlarged nucleus

References:

Genes: