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Haploid genotype - cdc2-33(A177T aa)

Genotype summary

Description
cdc2-33(A177T aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-33A177Tamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0004596 - abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete rereplication

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FYPO:0000502 - abnormally arrested mitotic cell cycle progression

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FYPO:0003379 - abolished meiosis II

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FYPO:0002044 - abolished premeiotic DNA replication

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FYPO:0001384 - abolished protein kinase activity

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FYPO:0002033 - abolished protein phosphorylation during vegetative growth

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0003436 - decreased protein kinase activity during mitotic G2 phase

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0001128 - decreased septation index

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000836 - increased protein level

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0001890 - increased RNA level

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FYPO:0000839 - inviable elongated mononucleate aseptate cell

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0000333 - mitotic G1/S phase transition delay

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FYPO:0003246 - normal mitotic S phase progression

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FYPO:0004962 - normal protein localization to chromatin at replication origin

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FYPO:0000776 - normal protein phosphorylation during vegetative growth

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0000840 - normal RNA level

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FYPO:0006506 - normal RNA level during mitotic G1 phase

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FYPO:0006158 - normal RNA level during mitotic S phase

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FYPO:0004235 - normal RNA level oscillation during mitotic cell cycle

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FYPO:0003503 - normal vegetative cell length

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

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