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Haploid genotype - cdc2-3w(C67Y aa) cdc25delta

Genotype summary

Description
cdc2-3w(C67Y aa) cdc25delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-3wC67Yamino_acid_mutationNot assayed or wild type
cdc25 (SPAC24H6.05)protein tyrosine phosphatase (M phase inducer) Cdc25cdc25deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0001933 - abnormal mitotic cell cycle regulation during cellular response to hydroxyurea

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000420 - delayed onset of cytokinesis

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FYPO:0008213 - increased vegetative cell population growth on lactate carbon source

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FYPO:0003012 - mitosis with unreplicated DNA

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FYPO:0001046 - premature mitosis

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FYPO:0002806 - sensitive to arsenate

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FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

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