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Haploid genotype - cdc2-DL41(P162L aa)[Overexpression]

Genotype summary

Description
cdc2-DL41(P162L aa)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-DL41P162Lamino_acid_mutationOverexpression

Annotation

Single locus phenotype

FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

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FYPO:0003738 - abnormal mitotic cell cycle arrest with condensed chromosomes

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FYPO:0004719 - abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell

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FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0005710 - abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest

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FYPO:0000117 - abnormal septum assembly

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0003758 - mitotic spindle elongation without chromosome separation

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