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Haploid genotype - cdc2-M26(P137S aa)

Genotype summary

Description
cdc2-M26(P137S aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-M26P137Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003449 - abnormal cell cycle arrest at mitotic G1/S phase transition

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FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0006563 - abolished MBF complex assembly during mitotic G1 phase

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FYPO:0000474 - abolished meiosis

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FYPO:0003378 - abolished meiosis I

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FYPO:0002044 - abolished premeiotic DNA replication

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FYPO:0003437 - abolished protein kinase activity during mitotic G1 phase

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FYPO:0000556 - abolished re-entry into mitotic cell cycle after pheromone arrest

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0004111 - decreased protein phosphorylation during mitotic G2 phase

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0005993 - normal cytoplasmic translation

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FYPO:0003246 - normal mitotic S phase progression

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0006506 - normal RNA level during mitotic G1 phase

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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