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Haploid genotype - cdc2-Y15F(aa)

Genotype summary

Description
cdc2-Y15F(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-Y15FY15Famino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000670 - abnormal mitotic sister chromatid separation

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FYPO:0007247 - abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation

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FYPO:0002044 - abolished premeiotic DNA replication

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FYPO:0002033 - abolished protein phosphorylation during vegetative growth

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FYPO:0001052 - cut, small cell

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FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004628 - delayed onset of premeiotic DNA replication

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0000377 - increased frequency of apoptosis

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FYPO:0001046 - premature mitosis

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002342 - septated vegetative cell

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FYPO:0006822 - viable small vegetative cell with normal cell growth rate

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