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Haploid genotype - cdc2-as(F84G aa)

Genotype summary

Description
cdc2-as(F84G aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc2 (SPBC11B10.09)cyclin-dependent protein kinase Cdk1/Cdc2cdc2-asF84Gamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0006175 - abnormal protein localization to centromere during mitotic metaphase

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FYPO:0001269 - abolished protein localization to kinetochore during vegetative growth

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FYPO:0002033 - abolished protein phosphorylation during vegetative growth

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FYPO:0008047 - decreased histone H3-K4 dimethylation at centromere during meiosis

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0000940 - decreased protein localization to mitotic spindle pole body

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FYPO:0005672 - decreased protein localization to nucleus during mitosis

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FYPO:0006185 - decreased protein localization to nucleus during prophase I

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FYPO:0002679 - decreased protein phosphorylation

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FYPO:0005577 - decreased protein phosphorylation during meiotic cell cycle

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0002536 - delayed onset of protein localization to nucleoplasm during cellular response to hydrogen peroxide

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FYPO:0008106 - increased cell size during stationary phase

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FYPO:0008048 - increased histone H3-K4 dimethylation at centromere during meiosis

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FYPO:0004635 - increased protein localization to mitotic spindle

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FYPO:0000252 - increased spontaneous diploidization

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FYPO:0004162 - loss of viability upon glucose starvation

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FYPO:0007664 - mononucleate monoseptate vegetative cell with anucleate compartment

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FYPO:0006832 - premature primary cell septum biogenesis

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FYPO:0002874 - premature protein localization to medial cortex during vegetative growth

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FYPO:0004383 - premature protein localization to mitotic spindle

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FYPO:0006824 - premature protein localization to mitotic spindle pole body

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FYPO:0007743 - premature septum assembly during mitotic interphase

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