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Haploid genotype - cdc20-P287R(aa)

Genotype summary

Description
cdc20-P287R(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc20 (SPBC25H2.13c)DNA polymerase epsilon catalytic subunit Pol2cdc20-P287RP287Ramino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000173 - abnormal mitotic cell cycle DNA replication checkpoint

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FYPO:0003923 - decreased rate of mitotic DNA replication elongation

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0001707 - increased mitotic DNA damage checkpoint activation

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FYPO:0002573 - increased number of Ssb1 foci

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FYPO:0000256 - mutator

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FYPO:0005753 - normal cellular dNTP level

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FYPO:0002578 - resistance to hydroxyurea

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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