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Haploid genotype - cdc20-P7(unknown)

Genotype summary

Description
cdc20-P7(unknown)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc20 (SPBC25H2.13c)DNA polymerase epsilon catalytic subunit Pol2cdc20-P7unknownunknownNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0001343 - abnormal mitotic DNA replication

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FYPO:0003485 - abolished DNA synthesis

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FYPO:0001978 - bent mitotic spindle

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0004475 - decreased mitotic DNA replication initiation

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FYPO:0004904 - decreased protein localization to centromere central core during vegetative growth

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FYPO:0005773 - elongated mononucleate aseptate vegetative cell

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FYPO:0006353 - increased centromere central core transcript level

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FYPO:0004237 - increased protein localization to heterochromatin at centromere outer repeat region

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FYPO:0003410 - increased spatial extent of CENP-A containing chromatin assembly

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0004909 - loss of punctate nuclear protein localization, with protein distributed in nucleus

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0001383 - normal DNA content

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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