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Haploid genotype - cdc20-ct1(Y1520N,D1625G,L1726S,S1904P aa)

Genotype summary

Description
cdc20-ct1(Y1520N,D1625G,L1726S,S1904P aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdc20 (SPBC25H2.13c)DNA polymerase epsilon catalytic subunit Pol2cdc20-ct1Y1520N,D1625G,L1726S,S1904Pamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0006727 - abolished mitotic DNA replication elongation

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0006731 - decreased CMG complex progression from replication origin

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0006729 - decreased protein localization to chromatin distal to replication origin

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0003923 - decreased rate of mitotic DNA replication elongation

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004961 - increased protein localization to chromatin at replication origin

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0006726 - normal CMG complex assembly

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FYPO:0004962 - normal protein localization to chromatin at replication origin

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FYPO:0000703 - normal protein-protein interaction

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