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Haploid genotype - cdc21-M68(unknown)

Genotype summary

Description
cdc21-M68(unknown)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mcm4 (SPCC16A11.17)MCM complex subunit Mcm4/Cdc21cdc21-M68unknownunknownNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0001277 - abolished MCM complex assembly

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FYPO:0001424 - abolished protein localization to nucleus during vegetative growth

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FYPO:0004550 - abolished protein phosphorylation during cellular response to hydroxyurea

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000470 - decreased mating type switching

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FYPO:0001982 - decreased rate of DNA replication during vegetative growth

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FYPO:0005773 - elongated mononucleate aseptate vegetative cell

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FYPO:0007380 - elongated T-shaped vegetative cell

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FYPO:0001740 - increased gross chromosomal rearrangement

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FYPO:0002596 - increased histone H2A phosphorylation during vegetative growth

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0005068 - increased number of double-strand break sites during mitotic S phase

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FYPO:0000455 - increased number of double-strand break sites during vegetative growth

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002573 - increased number of Ssb1 foci

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FYPO:0000786 - increased plasmid loss

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FYPO:0003011 - increased protein localization to chromatin during vegetative growth

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0000839 - inviable elongated mononucleate aseptate cell

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0001532 - normal duration of mitotic S phase

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000478 - normal meiosis

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FYPO:0001513 - normal mitotic sister chromatid segregation

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FYPO:0002043 - normal premeiotic DNA replication

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FYPO:0007880 - normal protein degradation during cellular response to methyl methanesulfonate

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0002635 - normal protein ubiquitination during vegetative growth

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FYPO:0000943 - normal spore morphology

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000783 - protein mislocalized to cytoplasm during vegetative growth

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FYPO:0003612 - viable spore population

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