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Haploid genotype - cdk9-T120G(aa)

Genotype summary

Description
cdk9-T120G(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdk9 (SPBC32H8.10)P-TEFb-associated cyclin-dependent protein kinase Cdk9cdk9-T120GT120Gamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0001971 - abnormal cell separation after cytokinesis resulting in chained cells

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FYPO:0006020 - abnormal protein distribution along RNA polymerase II-transcribed genes

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FYPO:0002577 - decreased chromatin binding

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FYPO:0004067 - decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth

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FYPO:0004161 - decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth

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FYPO:0002679 - decreased protein phosphorylation

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0006613 - decreased termination of RNA polymerase II transcription

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0002980 - increased chromatin binding

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0003086 - normal chromatin binding

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FYPO:0007347 - normal histone H3-K36 trimethylation during vegetative growth

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0004422 - normal protein phosphorylation

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FYPO:0001234 - slow vegetative cell population growth

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