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Haploid genotype - cdk9-T120G(aa) htb1-K119R(K120R aa)

Genotype summary

Description
cdk9-T120G(aa) htb1-K119R(K120R aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cdk9 (SPBC32H8.10)P-TEFb-associated cyclin-dependent protein kinase Cdk9cdk9-T120GT120Gamino_acid_mutationNot assayed or wild type
htb1 (SPCC622.09)histone H2B Htb1htb1-K119RK120Ramino_acid_mutationNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0006020 - abnormal protein distribution along RNA polymerase II-transcribed genes

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FYPO:0005516 - decreased nucleosome occupancy in euchromatin

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FYPO:0004161 - decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0005518 - increased histone H3-K14 acetylation at protein coding gene during vegetative growth

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FYPO:0004347 - increased histone H3-K9 acetylation at protein coding gene during vegetative growth

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FYPO:0007347 - normal histone H3-K36 trimethylation during vegetative growth

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