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Haploid genotype - cds1delta

Genotype summary

Description
cds1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cds1 (SPCC18B5.11c)DNA replication checkpoint kinase Cds1cds1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0001933 - abnormal mitotic cell cycle regulation during cellular response to hydroxyurea

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FYPO:0004254 - abnormal mitotic cell cycle regulation during cellular response to UV

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FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0006241 - abnormal negative regulation of mitotic DNA replication initiation during cellular response to DNA damage

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FYPO:0003067 - abnormal replication fork reversal

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FYPO:0006436 - abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0005165 - abnormal spatio-temporal regulation of replication fork localization

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FYPO:0004188 - abolished protein localization to nucleus during cellular response to hydroxyurea

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FYPO:0004550 - abolished protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003814 - abolished response to S-phase DNA damage checkpoint signaling

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FYPO:0000229 - cut

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0001053 - cut, normal size cell

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0004194 - decreased protein level during cellular response to hydroxyurea

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002976 - decreased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea

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FYPO:0003068 - decreased protein localization to chromatin at replication forks during cellular response to hydroxyurea

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FYPO:0006321 - decreased protein localization to chromatin at stalled replication fork

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FYPO:0005338 - decreased protein localization to nucleus during cellular response to hydroxyurea

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001982 - decreased rate of DNA replication during vegetative growth

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FYPO:0003923 - decreased rate of mitotic DNA replication elongation

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FYPO:0006240 - decreased rate of mitotic DNA replication elongation during cellular response to DNA damage

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FYPO:0007255 - decreased replication fork processing

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FYPO:0006242 - decreased replication fork stalling during cellular response to DNA damage

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FYPO:0003815 - decreased response to S-phase DNA damage checkpoint signaling

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FYPO:0002975 - decreased RNA level during cellular response to hydroxyurea

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FYPO:0003142 - decreased RNA level during cellular response to methyl methanesulfonate

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0009109 - decreased vegetative cell population growth after short incubation in hydroxyurea

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FYPO:0006372 - incomplete meiotic chromosome segregation, with chromosomal bridge

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FYPO:0005292 - increased chromatin binding during cellular response to hydroxyurea

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FYPO:0000274 - increased duration of mitotic M phase

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0002608 - increased histone H2A phosphorylation during cellular response to hydroxyurea

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FYPO:0000455 - increased number of double-strand break sites during vegetative growth

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FYPO:0006678 - increased number of Rad52 foci during cellular response to chromium

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FYPO:0007550 - increased number of Rad52 foci during cellular response to hydroxyurea

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FYPO:0005296 - increased number of Rad52 foci during mitotic S phase

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002573 - increased number of Ssb1 foci

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FYPO:0001249 - increased origin firing efficiency

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FYPO:0007068 - increased origin firing efficiency in subtelomeric heterochromatin

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FYPO:0004189 - increased protein level during cellular response to hydroxyurea

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FYPO:0007551 - increased protein localization to chromatin during cellular response to hydroxyurea

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FYPO:0002096 - increased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0007814 - increased rate of mitotic DNA replication elongation during cellular response to hydroxyurea

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0005704 - loss of viability following cellular response to hydroxyurea

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FYPO:0000378 - normal apoptosis

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0003118 - normal cellular reactive oxygen species level during vegetative growth

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0006371 - normal duration of meiotic prophase I

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FYPO:0007479 - normal epigenetic heterochromatin inheritance

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0010017 - normal histone H2B-K33 acetylation during vegetative growth

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FYPO:0007249 - normal level of X-shaped replication intermediates

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FYPO:0000478 - normal meiosis

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FYPO:0004667 - normal meiotic sister chromatid cohesion at centromere

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FYPO:0003613 - normal meiotic sister chromatid cohesion during meiotic prophase I

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FYPO:0008078 - normal meiotic sister kinetochore association in meiotic metaphase I

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FYPO:0005180 - normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase

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FYPO:0006437 - normal mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0006865 - normal mitotic DNA damage checkpoint during cellular response to streptonigrin

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FYPO:0001513 - normal mitotic sister chromatid segregation

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FYPO:0002043 - normal premeiotic DNA replication

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FYPO:0005181 - normal protein degradation during cellular response to UV

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FYPO:0003144 - normal protein level during cellular response to methyl methanesulfonate

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FYPO:0003069 - normal protein localization to chromatin at replication forks during cellular response to hydroxyurea

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FYPO:0005236 - normal protein localization to chromatin at stalled replication fork

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FYPO:0002979 - normal protein localization to chromatin during cellular response to methyl methanesulfonate

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0005644 - normal protein localization to nucleus during cellular response to hydroxyurea

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FYPO:0005614 - normal protein phosphorylation during cellular response to bleomycin

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FYPO:0002899 - normal protein phosphorylation during cellular response to DNA damage

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003131 - normal protein phosphorylation during cellular response to ionizing radiation

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0004252 - normal regulation of DNA replication during replication fork arrest

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FYPO:0005107 - normal regulation of mitotic DNA replication initiation

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FYPO:0003035 - normal RNA level during cellular response to UV

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FYPO:0002052 - normal sporulation frequency

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FYPO:0002687 - normal telomere length during vegetative growth

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FYPO:0003503 - normal vegetative cell length

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0006272 - premature mitotic DNA replication initiation from late origin

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001103 - resistance to hydrogen peroxide

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003384 - sensitive to chromium

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000107 - sensitive to latrunculin A

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0000841 - sensitive to sodium dodecyl sulfate

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FYPO:0007812 - sensitive to stavudine

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0001491 - viable vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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