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Haploid genotype - chk1delta

Genotype summary

Description
chk1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
chk1 (SPCC1259.13)Chk1 protein kinasechk1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000151 - abnormal meiotic chromosome segregation

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FYPO:0005179 - abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase

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FYPO:0002900 - abnormal mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0000229 - cut

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0001053 - cut, normal size cell

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FYPO:0000080 - decreased cell population growth at low temperature

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FYPO:0004190 - decreased protein level during cellular response to ionizing radiation

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FYPO:0003143 - decreased protein level during cellular response to methyl methanesulfonate

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FYPO:0004464 - decreased protein phosphorylation during cellular response to camptothecin

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0004192 - decreased RNA level during cellular response to ionizing radiation

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FYPO:0003142 - decreased RNA level during cellular response to methyl methanesulfonate

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FYPO:0006372 - incomplete meiotic chromosome segregation, with chromosomal bridge

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FYPO:0009072 - increased cell population growth on lysine nitrogen source

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0002978 - increased protein localization to chromatin during cellular response to methyl methanesulfonate

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FYPO:0000650 - increased septation index

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FYPO:0006518 - loss of viability in G0

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0000674 - normal cell population growth at high temperature

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FYPO:0003118 - normal cellular reactive oxygen species level during vegetative growth

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FYPO:0001383 - normal DNA content

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0010017 - normal histone H2B-K33 acetylation during vegetative growth

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FYPO:0000478 - normal meiosis

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FYPO:0004014 - normal mitotic cell cycle regulation during cellular response to UV

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FYPO:0002043 - normal premeiotic DNA replication

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0005614 - normal protein phosphorylation during cellular response to bleomycin

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003131 - normal protein phosphorylation during cellular response to ionizing radiation

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0004252 - normal regulation of DNA replication during replication fork arrest

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FYPO:0001903 - normal septation index

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FYPO:0005166 - normal spatio-temporal regulation of replication fork localization

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FYPO:0002052 - normal sporulation frequency

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FYPO:0002687 - normal telomere length during vegetative growth

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FYPO:0003503 - normal vegetative cell length

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0009110 - normal vegetative cell population growth after short incubation in hydroxyurea

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FYPO:0004720 - normal viability following cellular response to heat shock

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FYPO:0003538 - premature meiosis I

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FYPO:0000067 - resistance to brefeldin A

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FYPO:0000763 - resistance to cadmium

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0001501 - sensitive to brefeldin A

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003840 - sensitive to carbendazim

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FYPO:0003384 - sensitive to chromium

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FYPO:0002167 - sensitive to ethyl methanesulfonate

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0001491 - viable vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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