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Haploid genotype - chp1-N59A(aa) clr4delta->clr4+(reintroduced clr4+)

Genotype summary

Description
chp1-N59A(aa) clr4delta->clr4+(reintroduced clr4+)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
chp1 (SPAC18G6.02c)heterochromatin (HP1) family chromodomain protein Chp1chp1-N59AN59Aamino_acid_mutationNot assayed or wild type
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4delta->clr4+reintroduced clr4+otherNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0003044 - abnormal heterochromatin assembly

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Genes:

FYPO:0000877 - decreased histone H3-K9 dimethylation at centromere during vegetative growth

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FYPO:0000220 - increased centromeric outer repeat transcript level

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FYPO:0000228 - lagging mitotic chromosomes

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