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Haploid genotype - clr3-735(D232N aa)

Genotype summary

Description
clr3-735(D232N aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr3 (SPBC800.03)SHREC complex histone deacetylase (class II) subunit, Clr3clr3-735D232Namino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0008157 - abnormal histone deacetylation at the silent mating-type locus during vegetative growth

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FYPO:0000853 - abnormal nucleosome positioning

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FYPO:0007336 - abolished chromatin silencing at silent mating-type cassette

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FYPO:0001168 - decreased ATPase activity

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0003704 - decreased histone deacetylase activity

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FYPO:0005845 - decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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FYPO:0005154 - decreased protein localization to heterochromatin at mat2P silent mating-type cassette

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0007891 - decreased spatial extent of mating-type region heterochromatin assembly

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FYPO:0005310 - increased histone H3-K14 acetylation during vegetative growth

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FYPO:0000487 - increased meiotic recombination

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FYPO:0005311 - normal histone H3-K4 methylation during vegetative growth

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FYPO:0003223 - normal histone H3-K9 acetylation during vegetative growth

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