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Haploid genotype - clr4-3FA(F256A,F310A,F427A aa)

Genotype summary

Description
clr4-3FA(F256A,F310A,F427A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4-3FAF256A,F310A,F427Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007334 - abolished chromatin silencing at centromere outer repeat

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FYPO:0007336 - abolished chromatin silencing at silent mating-type cassette

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FYPO:0005850 - abolished protein localization to heterochromatin at centromere outer repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0010068 - decreased histone H3-K14 ubiquitination at pericentric heterochromatin during vegetative growth

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FYPO:0000876 - decreased histone H3-K9 dimethylation during vegetative growth

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FYPO:0000883 - decreased histone H3-K9 trimethylation at centromere during vegetative growth

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FYPO:0004577 - decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0005847 - decreased histone methyltransferase activity (H3-K9 specific) activity

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FYPO:0008422 - decreased protein localization to pericentric heterochromatin

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FYPO:0001645 - decreased protein-protein interaction

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