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Haploid genotype - clr4-G378S(aa)

Genotype summary

Description
clr4-G378S(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4-G378SG378Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0002834 - decreased chromatin silencing at centromere

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0003571 - decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0005847 - decreased histone methyltransferase activity (H3-K9 specific) activity

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0000943 - normal spore morphology

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