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Haploid genotype - clr4-GS253(D253G,P254G,N255S,F256G aa)

Genotype summary

Description
clr4-GS253(D253G,P254G,N255S,F256G aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4-GS253D253G,P254G,N255S,F256Gamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007334 - abolished chromatin silencing at centromere outer repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0000876 - decreased histone H3-K9 dimethylation during vegetative growth

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FYPO:0000883 - decreased histone H3-K9 trimethylation at centromere during vegetative growth

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FYPO:0004577 - decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0005847 - decreased histone methyltransferase activity (H3-K9 specific) activity

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