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Haploid genotype - clr4-set(R406A,N409A,H410A aa)

Genotype summary

Description
clr4-set(R406A,N409A,H410A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr4 (SPBC428.08c)histone lysine H3-K9 methyltransferase (Suv39) Clr4clr4-setR406A,N409A,H410Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0005554 - abolished histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0004745 - abolished histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0006813 - abolished histone H3-K9 trimethylation at centromere inner repeat during vegetative growth

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FYPO:0005843 - abolished histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0001740 - increased gross chromosomal rearrangement

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FYPO:0006815 - increased histone H3-K14 acetylation at centromere inner repeat during vegetative growth

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FYPO:0000966 - increased histone H3-K14 acetylation at centromere outer repeat during vegetative growth

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FYPO:0006681 - increased histone H3-K9 acetylation at centromere inner repeat during vegetative growth

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FYPO:0006814 - increased histone H3-K9 acetylation at centromere outer repeat during vegetative growth

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