Haploid genotype - clr4delta leo1delta

Genotype summary

Description: clr4delta leo1delta
Organism: Schizosaccharomyces pombe (fission yeast)

Allele summary

gene	Product	Allele name	Description	Type	Expression
clr4 (SPBC428.08c)	histone lysine H3-K9 methyltransferase (Suv39) Clr4	clr4delta	deletion	deletion	Null
leo1 (SPBC13E7.08c)	RNA polymerase II associated Paf1 complex subunit Leo1	leo1delta	deletion	deletion	Null

Annotation

Multi-locus phenotype

FYPO:0004542 - increased chromatin silencing at subtelomere

References:

PMID:29214404

Genes:

FYPO:0001740 - increased gross chromosomal rearrangement

References:

PMID:30652128

Genes:

FYPO:0001742 - increased isochromosome formation

References:

PMID:41525994

Genes:

FYPO:0007227 - increased number of R-loops at centromere

References:

PMID:41525994

Genes:

FYPO:0006368 - normal spatial extent of centromeric heterochromatin assembly

References:

PMID:29214404

Genes: