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Haploid genotype - clr6-1(G269D aa)[Knockdown] lsd1-deltaHMG(841-1000 Δaa)[Knockdown]

Genotype summary

Description
clr6-1(G269D aa)[Knockdown] lsd1-deltaHMG(841-1000 Δaa)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
clr6 (SPBC36.05c)histone deacetylase (class I) H3-K9 specific complex subunit Clr6clr6-1G269Damino_acid_mutationKnockdown
lsd1 (SPBC146.09c)histone demethylase SWIRM1lsd1-deltaHMG841-1000partial_amino_acid_deletionKnockdown

Annotation

Multi-locus phenotype

FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0005922 - decreased heterochromatin assembly at subtelomere

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FYPO:0007339 - increased cen-dg RNA level

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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