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Haploid genotype - crb2-2AQ(T73A,S80A aa)

Genotype summary

Description
crb2-2AQ(T73A,S80A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
crb2 (SPBC342.05)BRCT and tudor domain DNA checkpoint protein Crb2crb2-2AQT73A,S80Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003489 - abnormal mitotic cell cycle regulation during cellular response to ionizing radiation

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FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0002897 - decreased protein phosphorylation during cellular response to DNA damage

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FYPO:0003129 - loss of punctate nuclear protein localization during cellular response to ionizing radiation

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0003132 - normal punctate nuclear localization during cellular response to ionizing radiation

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FYPO:0003130 - premature mitotic G1 phase entry during cellular response to ionizing radiation

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000268 - sensitive to UV during vegetative growth

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