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Haploid genotype - crb2-K619M(aa) crb2-T215A(aa)

Genotype summary

Description
crb2-K619M(aa) crb2-T215A(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
crb2 (SPBC342.05)BRCT and tudor domain DNA checkpoint protein Crb2crb2-K619MK619Mamino_acid_mutationNot assayed or wild type
crb2 (SPBC342.05)BRCT and tudor domain DNA checkpoint protein Crb2crb2-T215AT215Aamino_acid_mutationNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0004869 - decreased number of Crb2 foci during cellular response to ionizing radiation

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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