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Haploid genotype - crb2delta

Genotype summary

Description
crb2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
crb2 (SPBC342.05)BRCT and tudor domain DNA checkpoint protein Crb2crb2deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0001933 - abnormal mitotic cell cycle regulation during cellular response to hydroxyurea

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FYPO:0003489 - abnormal mitotic cell cycle regulation during cellular response to ionizing radiation

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FYPO:0004254 - abnormal mitotic cell cycle regulation during cellular response to UV

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FYPO:0004259 - abolished mitotic G2 DNA damage checkpoint

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FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0002898 - abolished protein phosphorylation during cellular response to DNA damage

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FYPO:0002471 - abolished protein phosphorylation during cellular response to ionizing radiation

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FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

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FYPO:0000229 - cut

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0000250 - decreased cell population growth on proline nitrogen source

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FYPO:0000708 - decreased mating efficiency

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FYPO:0004464 - decreased protein phosphorylation during cellular response to camptothecin

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FYPO:0004228 - decreased protein phosphorylation during cellular response to UV

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FYPO:0006494 - decreased rDNA copy number during vegetative growth

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0004251 - increased DNA resection during replication fork processing

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FYPO:0003584 - increased double-strand break repair via nonhomologous end joining

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0001383 - normal DNA content

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0003906 - normal growth on bleomycin

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0005180 - normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0005614 - normal protein phosphorylation during cellular response to bleomycin

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0000776 - normal protein phosphorylation during vegetative growth

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FYPO:0002687 - normal telomere length during vegetative growth

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001453 - resistance to ethanol

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0007933 - sensitive to 2,2′-dipyridyl

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003384 - sensitive to chromium

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0001719 - sensitive to lithium

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0001457 - sensitive to tunicamycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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