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Haploid genotype - ctp1delta exo1delta pku80delta

Genotype summary

Description
ctp1delta exo1delta pku80delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ctp1 (SPCC338.08)endonuclease activator Ctp1ctp1deltadeletiondeletionNull
exo1 (SPBC29A10.05)exonuclease I Exo1exo1deltadeletiondeletionNull
pku80 (SPBC543.03c)Ku domain helicase (human XRCC5 ortholog) Pku80pku80deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0006687 - decreased DNA double-strand break processing during double-strand break repair via homologous recombination

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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