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Haploid genotype - ctp1delta pku80delta

Genotype summary

Description
ctp1delta pku80delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ctp1 (SPCC338.08)endonuclease activator Ctp1ctp1deltadeletiondeletionNull
pku80 (SPBC543.03c)Ku domain helicase (human XRCC5 ortholog) Pku80pku80deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0006687 - decreased DNA double-strand break processing during double-strand break repair via homologous recombination

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FYPO:0002474 - decreased protein localization to double-strand break site

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004229 - normal growth during cellular response to ionizing radiation

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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