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Haploid genotype - cut9-665(A535T aa)

Genotype summary

Description
cut9-665(A535T aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
cut9 (SPAC6F12.15c)anaphase-promoting complex TPR lobe subcomplex subunit Cut9/Apc6cut9-665A535Tamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

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FYPO:0002346 - abnormal chromatin silencing at centromere outer repeat

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FYPO:0000156 - abnormal chromatin silencing at silent mating-type cassette

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FYPO:0001946 - abolished mitotic sister chromatid separation

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003352 - decreased DNA double-strand break formation at mating-type locus

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FYPO:0000877 - decreased histone H3-K9 dimethylation at centromere during vegetative growth

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FYPO:0002355 - decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004198 - decreased protein degradation during mitosis

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FYPO:0003681 - decreased protein level at centromere outer repeat heterochromatin

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FYPO:0005102 - decreased protein level at silent mating-type cassette

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FYPO:0005004 - decreased protein level in anaphase-promoting complex

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001861 - increased minichromosome loss upon segregation during vegetative growth

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FYPO:0004157 - increased protein level during mitosis

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0002303 - inviable mononucleate monoseptate vegetative cell with anucleate compartment

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0006339 - mononucleate vegetative cell with mislocalized nucleus

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FYPO:0003166 - monoseptate vegetative cell with binucleate and anucleate compartments

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0003250 - premature septum assembly

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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