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Haploid genotype - dcr1delta

Genotype summary

Description
dcr1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
dcr1 (SPCC188.13c)dicerdcr1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0007645 - abnormal chromosome segregation during G1 to G0 transition

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FYPO:0000427 - abnormal G1 to G0 transition

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FYPO:0004814 - abnormal termination of RNA polymerase II transcription at highly transcribed protein-coding genes

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FYPO:0004812 - abnormal termination of RNA polymerase II transcription at rDNA

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FYPO:0004813 - abnormal termination of RNA polymerase II transcription at tDNA

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FYPO:0001934 - abolished cell population growth on glycerol carbon source

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FYPO:0001093 - abolished chromatin binding

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FYPO:0005554 - abolished histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0006112 - abolished histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0006111 - abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0002566 - abolished histone H3-K9 methylation during vegetative growth

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FYPO:0003744 - abolished protein localization to centromeric chromatin during vegetative growth

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FYPO:0005850 - abolished protein localization to heterochromatin at centromere outer repeat

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FYPO:0003074 - abolished protein localization to pericentric heterochromatin during vegetative growth

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0008011 - abolished siRNA loading onto RITS complex

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FYPO:0002835 - centromeric outer repeat transcript-derived siRNA absent

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FYPO:0000273 - centromeric outer repeat transcripts absent

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0000080 - decreased cell population growth at low temperature

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FYPO:0001407 - decreased cell population growth on glucose carbon source

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FYPO:0004201 - decreased centromeric outer repeat transcript-derived siRNA level

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FYPO:0002577 - decreased chromatin binding

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FYPO:0002834 - decreased chromatin silencing at centromere

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0003101 - decreased heterochromatin assembly at protein coding gene

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FYPO:0007009 - decreased heterochromatin assembly by small RNA

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FYPO:0000877 - decreased histone H3-K9 dimethylation at centromere during vegetative growth

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FYPO:0007643 - decreased histone H3-K9 dimethylation at centromere outer repeat during G0

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0007213 - decreased histone H3-K9 dimethylation at heterochromatin island during vegetative growth

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FYPO:0006269 - decreased histone H3-K9 dimethylation at protein coding gene during vegetative growth

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FYPO:0007644 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during G0

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0003571 - decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0000890 - decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0003103 - decreased mRNA-derived small RNA level

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FYPO:0004821 - decreased number of Rad52 foci at highly transcribed protein-coding genes

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FYPO:0000835 - decreased protein level

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FYPO:0000450 - decreased protein localization to centromere during vegetative growth

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FYPO:0002842 - decreased protein localization to centromere outer repeat

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0002391 - decreased protein localization to chromatin at rDNA

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0002134 - decreased protein-RNA interaction

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FYPO:0004817 - decreased rDNA antisense small RNA level

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FYPO:0004818 - decreased tDNA antisense small RNA level

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000429 - delayed G0 to G1 transition

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FYPO:0000998 - elongated cell during nitrogen starvation

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FYPO:0004808 - increased cellular protein aggregate level during cellular response to heat

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FYPO:0000220 - increased centromeric outer repeat transcript level

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FYPO:0002836 - increased centromeric outer repeat transcript-derived siRNA level

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FYPO:0004982 - increased centromeric transcript level

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FYPO:0002980 - increased chromatin binding

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FYPO:0008148 - increased CUT RNA level

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FYPO:0007639 - increased DNA damage at rDNA during G0

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FYPO:0001740 - increased gross chromosomal rearrangement

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FYPO:0004761 - increased histone exchange at pericentric heterochromatin

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FYPO:0002331 - increased histone H3-K4 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0007337 - increased histone H3-K4 methylation at centromere during vegetative growth

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FYPO:0000893 - increased histone H3-K9 acetylation at centromere during vegetative growth

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FYPO:0006814 - increased histone H3-K9 acetylation at centromere outer repeat during vegetative growth

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FYPO:0007640 - increased histone H3-K9 dimethylation at rDNA during G0

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FYPO:0007468 - increased histone H3-K9 dimethylation during G0

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FYPO:0002354 - increased level of heterochromatin-encoded proteins

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FYPO:0002664 - increased level of stress responsive gene mRNA during vegetative growth

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FYPO:0005995 - increased lncRNA level

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FYPO:0002564 - increased mature tRNA level during vegetative growth

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0004822 - increased number of R-loops at rDNA

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FYPO:0004819 - increased number of Rad52 foci at rDNA replication origins

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FYPO:0004820 - increased number of Rad52 foci at rDNA replication pause sites

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FYPO:0004710 - increased number of Rad52 foci during G0 to G1 transition

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FYPO:0004032 - increased protein localization to chromatin at rDNA

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0001890 - increased RNA level

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0005978 - increased spliced cen-dg RNA level

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FYPO:0004573 - increased telomeric transcript level

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0006518 - loss of viability in G0

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FYPO:0006660 - loss of viability upon G0 to G1 transition

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FYPO:0006996 - normal antisense RNA level

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FYPO:0000674 - normal cell population growth at high temperature

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FYPO:0004331 - normal chromatin silencing at centromere central core

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FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

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FYPO:0003555 - normal chromatin silencing at subtelomere

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0005866 - normal histone H3-K9 methylation at rDNA during vegetative growth

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FYPO:0005865 - normal histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0000472 - normal mating type switching

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FYPO:0000644 - normal protein localization during vegetative growth

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FYPO:0002625 - normal protein localization to chromatin rDNA

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FYPO:0004378 - normal protein localization to heterochromatin at silent mating-type cassette

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FYPO:0003576 - normal protein localization to subtelomeric heterochromatin

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0006368 - normal spatial extent of centromeric heterochromatin assembly

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FYPO:0000596 - normal transposition

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FYPO:0004826 - progressively decreasing rDNA copy number during successive meiotic generations

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FYPO:0000067 - resistance to brefeldin A

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0000096 - sensitive to cadmium

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0001719 - sensitive to lithium

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0006076 - siRNA absent from cell

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0004825 - stably decreased rDNA copy number during vegetative growth

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FYPO:0002112 - viable curved vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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