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Haploid genotype - ddb1delta spd1delta

Genotype summary

Description
ddb1delta spd1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ddb1 (SPAC17H9.10c)Cul4-RING E3 complex WD repeat protein subunit Ddb1ddb1deltadeletiondeletionNull
spd1 (SPAC29B12.03)ribonucleotide reductase (RNR) inhibitorspd1deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0002553 - abnormal double-strand break processing

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FYPO:0004188 - abolished protein localization to nucleus during cellular response to hydroxyurea

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0004137 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0004545 - decreased proteasomal ubiquitin-dependent protein degradation

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FYPO:0004066 - increased protein localization to chromatin at protein coding gene

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FYPO:0004377 - increased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0004380 - increased protein localization to pericentric heterochromatin during vegetative growth

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0002358 - normal histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004378 - normal protein localization to heterochromatin at silent mating-type cassette

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FYPO:0000590 - normal sporulation

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0005750 - sensitive to Zeocin

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