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Haploid genotype - dis1-6A(T279A,S293A,S300A,S551A,S556A,S590A aa)

Genotype summary

Description
dis1-6A(T279A,S293A,S300A,S551A,S556A,S590A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
dis1 (SPCC736.14)TOG/XMAP215 microtubule plus end tracking polymerase Dis1dis1-6AT279A,S293A,S300A,S551A,S556A,S590Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003350 - abolished protein localization to mitotic spindle midzone during anaphase B

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FYPO:0002678 - abolished protein phosphorylation

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FYPO:0007244 - decreased protein localization to kinetochore during mitotic metaphase

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FYPO:0001861 - increased minichromosome loss upon segregation during vegetative growth

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0004310 - normal duration of mitotic M phase

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FYPO:0006641 - normal protein localization to kinetochore during mitotic metaphase

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FYPO:0000091 - sensitive to thiabendazole

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