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Haploid genotype - dna2-L1097S(aa)

Genotype summary

Description
dna2-L1097S(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
dna2 (SPBC16D10.04c)DNA replication endonuclease-helicase Dna2dna2-L1097SL1097Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003067 - abnormal replication fork reversal

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0000185 - decreased gene conversion during vegetative growth

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FYPO:0004516 - decreased number of Rad52 foci during vegetative growth

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FYPO:0002474 - decreased protein localization to double-strand break site

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FYPO:0005786 - decreased spatial extent of double-strand break processing

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0005452 - increased break-induced loss of heterozygosity

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FYPO:0003584 - increased double-strand break repair via nonhomologous end joining

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0003069 - normal protein localization to chromatin at replication forks during cellular response to hydroxyurea

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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