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Haploid genotype - dpb3delta

Genotype summary

Description
dpb3delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
dpb3 (SPCC16C4.22)DNA polymerase epsilon Dpb3dpb3deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0000452 - abnormal protein localization to chromatin during vegetative growth

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FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0000890 - decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0000893 - increased histone H3-K9 acetylation at centromere during vegetative growth

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FYPO:0004742 - normal chromatin silencing at centromere outer repeat

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FYPO:0002060 - viable vegetative cell population

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