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Haploid genotype - dpb4delta

Genotype summary

Description
dpb4delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
dpb4 (SPBC3D6.09)DNA polymerase epsilon subunit Dpb4dpb4deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0000890 - decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0003938 - increased cell population growth during glucose starvation

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0009096 - increased cell population growth on xylose carbon source

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0006518 - loss of viability in G0

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FYPO:0004742 - normal chromatin silencing at centromere outer repeat

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0008186 - normal histone H3-K9 trimethylation at centromere central core during vegetative growth

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FYPO:0008199 - normal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0000067 - resistance to brefeldin A

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FYPO:0000763 - resistance to cadmium

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0002578 - resistance to hydroxyurea

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FYPO:0001583 - resistance to lithium

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FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000725 - resistance to methyl methanesulfonate

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FYPO:0009039 - resistance to potassium chloride

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0001034 - resistance to tunicamycin

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FYPO:0007808 - resistance to valproic acid

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FYPO:0000830 - resistance to vanadate

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FYPO:0000799 - sensitive to diamide

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000111 - sensitive to rapamycin

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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