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Haploid genotype - end4delta

Genotype summary

Description
end4delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
end4 (SPAC688.11)actin filament endocytic membrane adaptor End4end4deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000743 - abnormal actin cortical patch internalization

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FYPO:0000182 - abnormal cell wall organization during vegetative growth

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FYPO:0000034 - abnormal endocytosis during vegetative growth

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FYPO:0006497 - abnormal plasma membrane phosphatidylserine distribution

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FYPO:0000135 - abnormal plasma membrane sterol distribution

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FYPO:0001118 - abnormal vegetative cell morphology

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FYPO:0000421 - abolished endocytosis during vegetative growth

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FYPO:0003209 - abolished protein localization to cell tip, with protein mislocalized to cytoplasm

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FYPO:0000015 - branched vegetative cell

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0000251 - decreased cell population growth on galactose carbon source

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FYPO:0000684 - decreased cell population growth on glycerol carbon source

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FYPO:0000303 - decreased conjugation frequency

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FYPO:0004446 - decreased endocytosis during meiotic cell cycle

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FYPO:0000422 - decreased endocytosis during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0004443 - decreased protein localization to prospore membrane during meiosis II

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FYPO:0006589 - decreased protein localization to shmoo tip membrane, with protein distributed in plasma membrane

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FYPO:0000538 - decreased protein secretion during vegetative growth

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FYPO:0005801 - decreased rate of protein movement within plasma membrane at cell tip

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FYPO:0000584 - decreased sporulation frequency

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0002297 - dispersed actin cortical patch localization during mitotic interphase

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FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

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FYPO:0003504 - increased protein level in plasma membrane

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FYPO:0002852 - increased protein localization to cell tip during vegetative growth

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FYPO:0004967 - increased vegetative cell population growth during phosphate starvation

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FYPO:0002200 - inviable stubby septated vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0000224 - lemon-shaped cell

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0002436 - misoriented actin cables

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FYPO:0001019 - monopolar actin cortical patch localization during vegetative growth

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FYPO:0003028 - normal actin cortical patch localization during mitosis

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FYPO:0002424 - normal actin cortical patch localization during mitotic interphase

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FYPO:0000899 - normal microtubule cytoskeleton organization during vegetative growth

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0000644 - normal protein localization during vegetative growth

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FYPO:0008003 - normal protein localization to site of mechanical stress

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FYPO:0005806 - normal rate of protein movement within plasma membrane at cell side

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FYPO:0002717 - normal vacuole fusion during cellular hypotonic response

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FYPO:0001120 - pear-shaped vegetative cell

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FYPO:0004447 - protein mislocalized to prospore membrane

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0002642 - sensitive to amphotericin B

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FYPO:0000098 - sensitive to calcium

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FYPO:0001190 - sensitive to cell wall-degrading enzymes

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FYPO:0002640 - sensitive to clotrimazole

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FYPO:0001987 - sensitive to high pH

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FYPO:0003494 - sensitive to L-azetidine-2-carboxylic acid

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FYPO:0002641 - sensitive to micafungin

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FYPO:0003358 - sensitive to miconazole

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FYPO:0000086 - sensitive to tacrolimus

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0000281 - small vacuoles present in increased numbers during vegetative growth

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FYPO:0000021 - spheroid vegetative cell

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FYPO:0000024 - stubby vegetative cell

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FYPO:0000647 - vegetative cell lysis

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FYPO:0002903 - viable pear-shaped vegetative cell

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FYPO:0002106 - viable stubby vegetative cell

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FYPO:0002197 - viable vegetative cell with abnormal cell shape

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