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Haploid genotype - epe1delta lsd1-deltaHMG(841-1000 Δaa)[Knockdown]

Genotype summary

Description
epe1delta lsd1-deltaHMG(841-1000 Δaa)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
epe1 (SPCC622.16c)histone demethylase-like, Jmjc domain Epe1epe1deltadeletiondeletionNull
lsd1 (SPBC146.09c)histone demethylase SWIRM1lsd1-deltaHMG841-1000partial_amino_acid_deletionKnockdown

Annotation

Multi-locus phenotype

FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0005922 - decreased heterochromatin assembly at subtelomere

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0002355 - decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004137 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0007339 - increased cen-dg RNA level

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FYPO:0006110 - increased silent mating-type cassette transcript-derived siRNA level

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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