Haploid genotype - epr1-FFAT(F362A aa)[Overexpression]
Genotype summary
Description
epr1-FFAT(F362A aa)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)
Allele summary
gene
Product
Allele name
Description
Type
Expression
epr1 (SPAC6B12.08)
Atg8-interacting ER-phagy receptor Epr1
epr1-FFAT
F362A
amino_acid_mutation
Overexpression
Annotation
Single locus phenotype
FYPO:0007449
-
abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm
References:
PMID:32735772
Genes:
epr1 (SPAC6B12.08)
FYPO:0000705
-
abolished protein-protein interaction
References:
PMID:32735772
Genes:
epr1 (SPAC6B12.08)
FYPO:0007446
-
decreased reticulophagy during cellular response to endoplasmic reticulum stress
References:
PMID:32735772
Genes:
epr1 (SPAC6B12.08)
FYPO:0000843
-
sensitive to dithiothreitol
References:
PMID:32735772
Genes:
epr1 (SPAC6B12.08)