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Haploid genotype - eso1-G799D(aa)

Genotype summary

Description
eso1-G799D(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
eso1 (SPBC16A3.11)mitotic cohesin N-acetyltransferase/DNA polymerase eta Eso1 fusion proteineso1-G799DG799Damino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000209 - abnormal attachment of spindle microtubules to kinetochore during meiosis I

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FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

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FYPO:0002553 - abnormal double-strand break processing

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FYPO:0002092 - abnormal meiotic sister chromatid cohesion

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FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0006424 - abolished meiotic sister chromatid cohesion at centromere during meiosis I

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FYPO:0002393 - abolished protein acetylation during vegetative growth

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0002395 - decreased maintenance of protein localization to pericentric heterochromatin at centromere outer repeat

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FYPO:0001128 - decreased septation index

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FYPO:0000158 - DNA content increased during vegetative growth

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FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

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FYPO:0001490 - inviable elongated vegetative cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0002360 - normal chromatin silencing at centromere

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FYPO:0001689 - normal growth on 4-nitroquinoline N-oxide

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FYPO:0005313 - normal maintenance of mitotic sister chromatid cohesion

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FYPO:0006428 - normal mitotic sister chromatid biorientation

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FYPO:0002389 - normal protein localization to heterochromatin at centromere outer repeat

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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