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Haploid genotype - exo1delta mre11-RRRR(C454R,L455R,C479R,V480R aa) pku80delta

Genotype summary

Description
exo1delta mre11-RRRR(C454R,L455R,C479R,V480R aa) pku80delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
exo1 (SPBC29A10.05)exonuclease I Exo1exo1deltadeletiondeletionNull
mre11 (SPAC13C5.07)Mre11 nucleasemre11-RRRRC454R,L455R,C479R,V480Ramino_acid_mutationNot assayed or wild type
pku80 (SPBC543.03c)Ku domain helicase (human XRCC5 ortholog) Pku80pku80deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000268 - sensitive to UV during vegetative growth

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