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Haploid genotype - hht1-Y41F(Y42F aa) hht2-Y41F(Y42F aa) hht3-Y41F(Y42F aa)

Genotype summary

Description
hht1-Y41F(Y42F aa) hht2-Y41F(Y42F aa) hht3-Y41F(Y42F aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hht1 (SPAC1834.04)histone H3 h3.1hht1-Y41FY42Famino_acid_mutationNot assayed or wild type
hht2 (SPBC8D2.04)histone H3 h3.2hht2-Y41FY42Famino_acid_mutationNot assayed or wild type
hht3 (SPBC1105.11c)histone H3 h3.3hht3-Y41FY42Famino_acid_mutationNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0006299 - increased chromatin silencing at centromere outer repeat

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FYPO:0004542 - increased chromatin silencing at subtelomere

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FYPO:0004380 - increased protein localization to pericentric heterochromatin during vegetative growth

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0003575 - normal histone H3-K9 acetylation at centromere outer repeat during vegetative growth

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FYPO:0006395 - normal histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0004743 - normal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0006429 - normal histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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