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Haploid genotype - hsk1-89(L339P,E403K,L416P aa)

Genotype summary

Description
hsk1-89(L339P,E403K,L416P aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hsk1 (SPBC776.12c)Dbf4(Dfp1)-dependent protein kinase Hsk1hsk1-89L339P,E403K,L416Pamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0001933 - abnormal mitotic cell cycle regulation during cellular response to hydroxyurea

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FYPO:0002196 - abnormal vegetative cell shape

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FYPO:0001093 - abolished chromatin binding

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FYPO:0005095 - abolished protein localization to chromatin at replication origin

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FYPO:0004550 - abolished protein phosphorylation during cellular response to hydroxyurea

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FYPO:0004660 - abolished protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0005093 - decreased duration of protein phosphorylation during cellular response to hydroxyurea

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FYPO:0005094 - decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea

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FYPO:0004240 - decreased histone H3-K56 acetylation during vegetative growth

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FYPO:0001250 - decreased origin firing efficiency

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FYPO:0007878 - decreased protein degradation during cellular response to methyl methanesulfonate

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0002097 - decreased protein kinase activity during cellular response to hydroxyurea

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0002470 - decreased protein phosphorylation during cellular response to ionizing radiation

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0002800 - normal protein degradation during vegetative growth

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FYPO:0003075 - normal protein kinase activity

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FYPO:0004548 - normal protein kinase activity during cellular response to hydroxyurea

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0004962 - normal protein localization to chromatin at replication origin

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000416 - premature mitotic sister chromatid separation

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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