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Haploid genotype - hst4delta

Genotype summary

Description
hst4delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hst4 (SPAC1783.04c)histone deacetylase, Sirtuin family, NAD-dependent Hst4hst4deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000059 - abnormal mitotic cell cycle

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FYPO:0004492 - abnormal RNA 5'-end processing

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FYPO:0000502 - abnormally arrested mitotic cell cycle progression

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FYPO:0000080 - decreased cell population growth at low temperature

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FYPO:0000684 - decreased cell population growth on glycerol carbon source

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0004491 - decreased nucleosome occupancy

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FYPO:0002902 - decreased protein localization to kinetochore during vegetative growth

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FYPO:0005545 - decreased Tf body formation

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FYPO:0007270 - decreased Tf body tethering to centromere

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004928 - fragmented DNA during vegetative growth

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FYPO:0008162 - increased activation of S-phase DNA damage checkpoint

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FYPO:0009093 - increased cell population growth on lysine and serine nitrogen source

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FYPO:0008270 - increased H3-K56 acetylation during vegetative growth

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FYPO:0000332 - increased histone acetylation during vegetative growth

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FYPO:0004489 - increased level of amino acid biosynthesis gene mRNA during vegetative growth

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FYPO:0001861 - increased minichromosome loss upon segregation during vegetative growth

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FYPO:0000239 - increased transcription from MCB promoter

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FYPO:0004672 - inviable elongated vegetative cell with fragmented nucleus

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FYPO:0007142 - loss of viability following cellular response to ionizing radiation

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0001925 - normal cellular response to gamma radiation

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FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0010017 - normal histone H2B-K33 acetylation during vegetative growth

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FYPO:0008160 - normal histone H3-K56 acetylation during vegetative growth

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FYPO:0003223 - normal histone H3-K9 acetylation during vegetative growth

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FYPO:0008161 - normal histone H4-K16 acetylation during vegetative growth

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FYPO:0009041 - resistance to 2,2′-dipyridyl

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FYPO:0000763 - resistance to cadmium

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0002693 - resistance to diamide

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0009034 - resistance to ethylenediaminetetraacetic acid

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FYPO:0001583 - resistance to lithium

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FYPO:0000830 - resistance to vanadate

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FYPO:0007921 - sensitive to benzamidine

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0009080 - sensitive to calcofluor and sodium dodecyl sulfate

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FYPO:0001188 - sensitive to Calcofluor White

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0000111 - sensitive to rapamycin

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0003656 - sensitive to vanadate

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0001492 - viable elongated vegetative cell

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FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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