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Haploid genotype - hta1-R18A(R19A aa) hta2-R18A(R19A aa) pht1+(wild type)[Knockdown]

Genotype summary

Description
hta1-R18A(R19A aa) hta2-R18A(R19A aa) pht1+(wild type)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hta1 (SPCC622.08c)histone H2A alphahta1-R18AR19Aamino_acid_mutationNot assayed or wild type
hta2 (SPAC19G12.06c)histone H2A betahta2-R18AR19Aamino_acid_mutationNot assayed or wild type
pht1 (SPBC11B10.10c)histone H2A variant H2A.Z Pht1pht1+wild typewild_typeKnockdown

Annotation

Multi-locus phenotype

FYPO:0001946 - abolished mitotic sister chromatid separation

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FYPO:0002909 - decreased protein localization to chromatin during vegetative growth

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FYPO:0001489 - inviable vegetative cell

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FYPO:0000228 - lagging mitotic chromosomes

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