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Haploid genotype - hta1-S129A(aa) hta2-S128A(aa)

Genotype summary

Description
hta1-S129A(aa) hta2-S128A(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hta1 (SPCC622.08c)histone H2A alphahta1-S129AS129Aamino_acid_mutationNot assayed or wild type
hta2 (SPAC19G12.06c)histone H2A betahta2-S128AS128Aamino_acid_mutationNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0003489 - abnormal mitotic cell cycle regulation during cellular response to ionizing radiation

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FYPO:0004870 - decreased duration of mitotic G2 DNA damage checkpoint

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FYPO:0004869 - decreased number of Crb2 foci during cellular response to ionizing radiation

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FYPO:0002679 - decreased protein phosphorylation

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FYPO:0002470 - decreased protein phosphorylation during cellular response to ionizing radiation

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FYPO:0003584 - increased double-strand break repair via nonhomologous end joining

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0003129 - loss of punctate nuclear protein localization during cellular response to ionizing radiation

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0004692 - normal protein localization to mitotic spindle midzone

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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