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Haploid genotype - htb1-G52D(G53D aa)

Genotype summary

Description
htb1-G52D(G53D aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
htb1 (SPCC622.09)histone H2B Htb1htb1-G52DG53Damino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0002340 - decreased DNA recombination during vegetative growth

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FYPO:0005159 - decreased DNA synthesis involved in mitotic DNA replication

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FYPO:0003912 - decreased double-strand break repair via homologous recombination

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FYPO:0005608 - decreased histone H2B-K119 ubiquitination at double-strand break site during vegetative growth

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FYPO:0007386 - decreased histone H2B-K119 ubiquitination during vegetative growth

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FYPO:0005677 - decreased number of Rad52 foci during mitotic S phase

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0004161 - decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0007881 - increased duration of histone H2A phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0004066 - increased protein localization to chromatin at protein coding gene

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000964 - normal growth on thiabendazole

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FYPO:0008250 - normal protein localization to chromatin at protein coding gene

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000084 - sensitive to 6-azauracil

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0003670 - sensitive to mycophenolic acid

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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