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Haploid genotype - htb1-G52D(G53D aa) shf1delta ubp8delta

Genotype summary

Description
htb1-G52D(G53D aa) shf1delta ubp8delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
htb1 (SPCC622.09)histone H2B Htb1htb1-G52DG53Damino_acid_mutationNot assayed or wild type
shf1 (SPAC22F8.12c)histone H2B-K119 ubiquitin ligase complex (HULC) subunit Shf1shf1deltadeletiondeletionNull
ubp8 (SPAC13A11.04c)SAGA complex ubiquitin C-terminal hydrolase Ubp8ubp8deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0002922 - abolished histone H2B-K119 ubiquitination during vegetative growth

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003912 - decreased double-strand break repair via homologous recombination

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002344 - sensitive to phleomycin

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