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Haploid genotype - htb1-K119R(K120R aa)

Genotype summary

Description
htb1-K119R(K120R aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
htb1 (SPCC622.09)histone H2B Htb1htb1-K119RK120Ramino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000854 - abnormal nucleosome positioning in euchromatin

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FYPO:0006020 - abnormal protein distribution along RNA polymerase II-transcribed genes

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FYPO:0002922 - abolished histone H2B-K119 ubiquitination during vegetative growth

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0005226 - decreased level of ubiquitinated protein in cell

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FYPO:0003151 - decreased protein level during cellular response to heat

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0004161 - decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001122 - elongated vegetative cell

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0005071 - increased chromatin silencing at centromere

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FYPO:0007835 - increased histone binding

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FYPO:0007836 - increased nucleosome occupancy at subtelomere

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FYPO:0007347 - normal histone H3-K36 trimethylation during vegetative growth

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0006986 - normal spatial extent of heterochromatin assembly to boundary element IRL

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FYPO:0001984 - protein absent from cell during vegetative growth

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FYPO:0007834 - protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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