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Haploid genotype - hus1delta

Genotype summary

Description
hus1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
hus1 (SPAC20G4.04c)checkpoint clamp complex protein Hus1hus1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0003489 - abnormal mitotic cell cycle regulation during cellular response to ionizing radiation

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FYPO:0005179 - abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase

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FYPO:0002517 - abnormal response to mitotic cell cycle checkpoint signaling

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FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0004262 - abolished protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation

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FYPO:0000229 - cut

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0001407 - decreased cell population growth on glucose carbon source

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FYPO:0000250 - decreased cell population growth on proline nitrogen source

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003142 - decreased RNA level during cellular response to methyl methanesulfonate

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FYPO:0003034 - decreased RNA level during cellular response to UV

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FYPO:0003938 - increased cell population growth during glucose starvation

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FYPO:0009052 - increased cell population growth on glutamate nitrogen source

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FYPO:0004167 - increased cell population growth on glycerol carbon source

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FYPO:0009072 - increased cell population growth on lysine nitrogen source

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FYPO:0009098 - increased cell population growth on mannitol carbon source

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0000377 - increased frequency of apoptosis

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0000650 - increased septation index

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FYPO:0006863 - loss of viability following cellular response to bleomycin

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FYPO:0006518 - loss of viability in G0

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FYPO:0000378 - normal apoptosis

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FYPO:0003118 - normal cellular reactive oxygen species level during vegetative growth

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001509 - normal protein localization to chromatin during vegetative growth

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003131 - normal protein phosphorylation during cellular response to ionizing radiation

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0003035 - normal RNA level during cellular response to UV

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FYPO:0000067 - resistance to brefeldin A

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0004432 - sensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone

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FYPO:0004431 - sensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone

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FYPO:0004434 - sensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000084 - sensitive to 6-azauracil

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003384 - sensitive to chromium

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FYPO:0000102 - sensitive to cisplatin

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002345 - sensitive to oxaliplatin

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0000111 - sensitive to rapamycin

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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